Welcome to RECON


designed by N. Sukumar, Dechuan Zhuang, William P. Katt, Christopher E. Whitehead and Curt Breneman
© Rensselaer Polytechnic Institute, 2001-2003

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RECON License

RECON is an algorithm for the rapid reconstruction of molecular charge densities and charge density-based electronic properties of molecules, using atomic charge density fragments precomputed from ab initio wavefunctions. The method is based on Bader's quantum theory of Atoms in Molecules.

A library of atomic charge density fragments has been built in a form that allows for the rapid retrieval of the fragments and molecular assembly. The RECON algorithm reads in a molecular database, determines atom types and environments, assigns the closest match from the library of atom types and combines the densities of the atomic fragments to compute a large set of new and traditional QSAR descriptors. QSPR and QSER indices for large pharmaceutical databases or proteins can be computed within seconds.

Interpretation of Molecular Descriptors